Molecular Playground/ClyA

About this Structure

Image:ClyA-monomer2.png

1QOY is a monomer from the dodecameric pore-forming toxin from Escherichia coli. It is comprised of four alpha helicies and a smaller fifth alpha helix.

Though its crystal structure,2WCD revealed a dodecamer, larger pores have been isolated, as well.

Image:ClyA.png Image:ClyA-protomer.png

Research on ClyA at UMass Amherst

The Chen Lab, in collaboration with the Heuck lab, recently published a paper on ClyA assembly.