About this Structure
Image:ClyA-monomer2.png
1QOY is a monomer from the dodecameric pore-forming toxin (PFT) from Escherichia coli. It is a 34kDa protein comprised of four alpha helicies, a smaller fifth alpha helix, and a beta tongue.
Though its crystal structure,2WCD revealed a dodecamer, larger pores have been isolated, as well.
Image:ClyA.png Image:ClyA-protomer.png
Research on ClyA at UMass Amherst
The Chen Lab, in collaboration with the Heuck lab, recently published a paper on ClyA assembly. Currently, we are investigating the forces that influence polymer translocation through ClyA.
