4ou9

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Template:STRUCTURE 4ou9

Contents

Crystal structure of apocarotenoid oxygenase in the presence of Triton X-100

Template:ABSTRACT PUBMED 24648526

Function

[ACOX_SYNY3] Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta-carotene or lycopene.

About this Structure

4ou9 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Sui X, Kiser PD, Che T, Carey PR, Golczak M, Shi W, Von Lintig J, Palczewski K. Analysis of carotenoid isomerase activity in a prototypical carotenoid cleavage enzyme, apocarotenoid oxygenase (ACO). J Biol Chem. 2014 Mar 19. PMID:24648526 doi:http://dx.doi.org/10.1074/jbc.M114.552836

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