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2md5

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Template:STRUCTURE 2md5

Contents

Structure of uninhibited ETV6 ETS domain

Template:ABSTRACT PUBMED 24333486

Function

[ETV6_MOUSE] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.

About this Structure

2md5 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • De S, Chan AC, Coyne HJ 3rd, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol. 2013 Dec 11. pii: S0022-2836(13)00747-X. doi:, 10.1016/j.jmb.2013.11.031. PMID:24333486 doi:http://dx.doi.org/10.1016/j.jmb.2013.11.031

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OCA

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