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4cqf

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Template:STRUCTURE 4cqf

Crystal structure of Schistosoma mansoni HDAC8 complexed with a mercaptoacetamide inhibitor

Template:ABSTRACT PUBMED 24657767

About this Structure

4cqf is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Stolfa DA, Marek M, Lancelot J, Hauser AT, Walter A, Leproult E, Melesina J, Rumpf T, Wurtz JM, Cavarelli J, Sippl W, Pierce RJ, Romier C, Jung M. Molecular basis for the anti-parasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen Schistosoma mansoni. J Mol Biol. 2014 Mar 20. pii: S0022-2836(14)00131-4. doi:, 10.1016/j.jmb.2014.03.007. PMID:24657767 doi:http://dx.doi.org/10.1016/j.jmb.2014.03.007

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