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3wdk

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Template:STRUCTURE 3wdk

Contents

Crystal structure of 4-phosphopantoate-beta-alanine ligase complexed with reaction intermediate

Template:ABSTRACT PUBMED 24638914

Function

[PPS_THEKO] Catalyzes the conversion of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway. Cannot use (R)-pantoate as substrate and thus does not display pantothenate synthetase (PS) activity.

About this Structure

3wdk is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Kishimoto A, Kita A, Ishibashi T, Tomita H, Yokooji Y, Imanaka T, Atomi H, Miki K. Crystal Structure of Phosphopantothenate Synthetase from Thermococcus k odakarensis. Proteins. 2014 Mar 17. doi: 10.1002/prot.24546. PMID:24638914 doi:http://dx.doi.org/10.1002/prot.24546

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OCA

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