Phosphate-binding protein

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Template:STRUCTURE 1pbp

Phosphate-binding protein (PBP) binds phosphate (Pi) with high affinity. PBP is involved in various biological processes like cell cycle regulation. PBP is produced under conditions of low Pi concentration. It binds Pi in the periplasm and transfers it to a membrane protein which transports it to the cytoplasm. PBP undergoes conformational change upon binding to Pi.

3D structures of phosphate-binding protein

Updated on 03-April-2014

1qui, 1oib - EcPBP (mutant) - Escherichia coli
4jwo – PBP – Planctomyces limnophilus
4exl, 4h1x – SpPBP – Streptococcus pneumoniae
1pbp, 2abh, 1ixh – EcPBP + Pi
1qui - EcPBP (mutant) + Br + Pi
1quj, 1qul - EcPBP (mutant) + Cl + Pi
1quk, 1ixi, 1ixg, 4a40 - EcPBP (mutant) + Pi
1a54, 1a55 - EcPBP (mutant) + dihydrogenphosphate
2v3q – hPBP + Pi – human
1pc3, 4lvq – PBP + Pi – Mycobacterium tuberculosis
3w9v, 3w9w – upPBP + Pi – unidentified prokaryote
4lat – SpPBP + Pi
4m1v - upPBP (mutant) + Pi

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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