1chz

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Template:STRUCTURE 1chz

Contents

A NEW NEUROTOXIN FROM BUTHUS MARTENSII KARSCH

Template:ABSTRACT PUBMED 10666623

Function

[SCM2_MESMA] Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals and insects.

About this Structure

1chz is a 1 chain structure with sequence from Mesobuthus martensii. Full crystallographic information is available from OCA.

Reference

  • He XL, Deng JP, Wang M, Zhang Y, Wang DC. Structure of a new neurotoxin from the scorpion Buthus martensii Karsch at 1.76 A. Acta Crystallogr D Biol Crystallogr. 2000 Jan;56(Pt 1):25-33. PMID:10666623

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