1p0z

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 1p0z

Contents 1 Sensor Kinase CitA binding domain 2 Function 3 About this Structure 4 Reference

Sensor Kinase CitA binding domain

Template:ABSTRACT PUBMED 12867417

Function

[CITA_KLEPN] Member of the two-component regulatory system CitA/CitB. Probably activates CitB by phosphorylation. The periplasmic domain binds H-citrate(2-), which is essential for induction of the citrate-fermentation genes.^[1]

About this Structure

1p0z is a 10 chain structure with sequence from "bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886. Full crystallographic information is available from OCA.

Reference

• Reinelt S, Hofmann E, Gerharz T, Bott M, Madden DR. The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain. J Biol Chem. 2003 Oct 3;278(40):39189-96. Epub 2003 Jul 16. PMID:12867417 doi:10.1074/jbc.M305864200

1. ↑ Kaspar S, Perozzo R, Reinelt S, Meyer M, Pfister K, Scapozza L, Bott M. The periplasmic domain of the histidine autokinase CitA functions as a highly specific citrate receptor. Mol Microbiol. 1999 Aug;33(4):858-72. PMID:10447894