4jba

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Template:STRUCTURE 4jba

Contents

Crystal Structure of the Oxidized Form of MarR from E.coli

Template:ABSTRACT PUBMED 24185215

Function

[MARR_ECOLI] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.

About this Structure

4jba is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

Reference

  • Hao Z, Lou H, Zhu R, Zhu J, Zhang D, Zhao BS, Zeng S, Chen X, Chan J, He C, Chen PR. The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli. Nat Chem Biol. 2014 Jan;10(1):21-8. doi: 10.1038/nchembio.1380. Epub 2013 Nov 3. PMID:24185215 doi:http://dx.doi.org/10.1038/nchembio.1380

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OCA

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