3pil

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Template:STRUCTURE 3pil

Contents

Crystal structure of Mxr1 from Saccharomyces cerevisiae in reduced form

Template:ABSTRACT PUBMED 21345799

Function

[MSRA_YEAST] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Also able to reduce dimethyl sulfoxide (DMSO) as well, with DMS as the product.

About this Structure

3pil is a 2 chain structure with sequence from Atcc 18824. Full crystallographic information is available from OCA.

Reference

  • Ma XX, Guo PC, Shi WW, Luo M, Tan XF, Chen Y, Zhou CZ. Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1. J Biol Chem. 2011 Apr 15;286(15):13430-7. Epub 2011 Feb 23. PMID:21345799 doi:http://dx.doi.org/10.1074/jbc.M110.205161

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