4lqc
From Proteopedia
The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry.
Template:ABSTRACT PUBMED 24275656
About this Structure
4lqc is a 2 chain structure with sequence from "micrococcus_melitensis"_(hughes_1893)_bruce_1893 "micrococcus melitensis" (hughes 1893) bruce 1893. Full crystallographic information is available from OCA.
Reference
- Snyder GA, Deredge D, Waldhuber A, Fresquez T, Wilkins DZ, Smith PT, Durr S, Cirl C, Jiang J, Jennings W, Luchetti T, Snyder N, Sundberg EJ, Wintrode P, Miethke T, Xiao TS. Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. J Biol Chem. 2014 Jan 10;289(2):669-79. doi: 10.1074/jbc.M113.523407. Epub 2013, Nov 25. PMID:24275656 doi:http://dx.doi.org/10.1074/jbc.M113.523407
Categories: Cirl, C. | Fresquez, T. | Jiang, J. | Luchetti, T. | Miethke, T. | Smith, P. | Snyder, G A. | Snyder, N. | Xiao, T S. | Bacterial tir like domain | Cytoplasmic | Flavodoxin fold | Immune system | Innate immunity | Myd88 | Myd88 binding | Proteolytic fragment from alpha 2 chymotrypsin | Tir | Tirap molecular mimic
