4ns5

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 4ns5

Contents 1 Crystal structure of human BS69 Bromo-Zinc finger-PWWP 2 Function 3 About this Structure 4 Reference

Crystal structure of human BS69 Bromo-Zinc finger-PWWP

Function

[ZMY11_HUMAN] Corepressor of transcription (Probable). May be involved in chromatin remodeling through association with several remodeling factors.^{[1] [2]}

About this Structure

4ns5 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

• Wang J, Qin S, Li F, Li S, Zhang W, Peng J, Zhang Z, Gong Q, Wu J, Shi Y. Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding. Cell Res. 2014 Mar 28. doi: 10.1038/cr.2014.38. PMID:24675531 doi:http://dx.doi.org/10.1038/cr.2014.38

1. ↑ Velasco G, Grkovic S, Ansieau S. New insights into BS69 functions. J Biol Chem. 2006 Jun 16;281(24):16546-50. Epub 2006 Mar 24. PMID:16565076 doi:http://dx.doi.org/10.1074/jbc.M600573200
2. ↑ Masselink H, Bernards R. The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR. Oncogene. 2000 Mar 16;19(12):1538-46. PMID:10734313 doi:http://dx.doi.org/10.1038/sj.onc.1203421