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4m5s

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Revision as of 06:43, 9 April 2014 by OCA (Talk | contribs)
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Template:STRUCTURE 4m5s

Contents

Human alphaB crystallin core domain in complex with C-terminal peptide

Disease

[CRYAB_HUMAN] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

[CRYAB_HUMAN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.

About this Structure

4m5s is a 2 chain structure. Full crystallographic information is available from OCA.

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