This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1a37
From Proteopedia
Contents |
14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE
Template:ABSTRACT PUBMED 9632691
Function
[1433Z_BOVIN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin.[1]
About this Structure
1a37 is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Petosa C, Masters SC, Bankston LA, Pohl J, Wang B, Fu H, Liddington RC. 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J Biol Chem. 1998 Jun 26;273(26):16305-10. PMID:9632691
