1b4q

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Template:STRUCTURE 1b4q

Contents

Solution structure of human thioltransferase complex with glutathione

Template:ABSTRACT PUBMED 9860827

Function

[GLRX1_HUMAN] Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

About this Structure

1b4q is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Yang Y, Jao S, Nanduri S, Starke DW, Mieyal JJ, Qin J. Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity. Biochemistry. 1998 Dec 8;37(49):17145-56. PMID:9860827 doi:10.1021/bi9806504

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