4azd

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Template:STRUCTURE 4azd

Contents

T57V mutant of aspartate decarboxylase

Template:ABSTRACT PUBMED 24699660

Function

[PAND_ECOLI] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.[1]

About this Structure

4azd is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

Reference

  • Webb ME, Yorke BA, Kershaw T, Lovelock S, Lobley CM, Kilkenny ML, Smith AG, Blundell TL, Pearson AR, Abell C. Threonine 57 is required for the post-translational activation of Escherichia coli aspartate alpha-decarboxylase. Acta Crystallogr D Biol Crystallogr. 2014 Apr 1;70(Pt 4):1166-72. doi:, 10.1107/S1399004713034275. Epub 2014 Mar 21. PMID:24699660 doi:http://dx.doi.org/10.1107/S1399004713034275
  1. Cronan JE Jr. Beta-alanine synthesis in Escherichia coli. J Bacteriol. 1980 Mar;141(3):1291-7. PMID:6767707

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