2rt3

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Template:STRUCTURE 2rt3

Contents

Solution structure of the second RRM domain of Nrd1

Template:ABSTRACT PUBMED 23770370

Function

[NRD1_SCHPO] Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes until cells reach a critical level of starvation. RNA-binding protein that preferentially binds poly(U).[1]

About this Structure

2rt3 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Kobayashi A, Kanaba T, Satoh R, Fujiwara T, Ito Y, Sugiura R, Mishima M. Structure of the second RRM domain of Nrd1, a fission yeast MAPK target RNA binding protein, and implication for its RNA recognition and regulation. Biochem Biophys Res Commun. 2013 Jul 19;437(1):12-7. doi:, 10.1016/j.bbrc.2013.06.008. Epub 2013 Jun 12. PMID:23770370 doi:http://dx.doi.org/10.1016/j.bbrc.2013.06.008
  1. ↑ Jeong HT, Ozoe F, Tanaka K, Nakagawa T, Matsuda H, Kawamukai M. A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe. Genetics. 2004 May;167(1):77-91. PMID:15166138

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