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4bpm
From Proteopedia
Contents |
Crystal structure of a human integral membrane enzyme
Function
[PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).[1]
About this Structure
4bpm is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Jegerschold C, Pawelzik SC, Purhonen P, Bhakat P, Gheorghe KR, Gyobu N, Mitsuoka K, Morgenstern R, Jakobsson PJ, Hebert H. Structural basis for induced formation of the inflammatory mediator prostaglandin E2. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11110-5. Epub 2008 Aug 5. PMID:18682561 doi:0802894105
Categories: Prostaglandin-E synthase | Caffrey, M. | Li, D. | Olieric, V. | Wang, M. | Anomalous dispersion | Cancer | Drug target | In meso crystallization | Inflammation | Inhibitor | Isomerase | Leukotriene c4 synthase | Lipid metabolism | Mapag | Membrane protein | Membrane-associated proteins in eicosanoid and glutathione metabolism | Microcrystal | Mpges1 | Pain | S-sad | Sulfur-sad
