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4nef
From Proteopedia
Contents |
X-ray structure of human Aquaporin 2
Disease
[AQP2_HUMAN] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.
Function
[AQP2_HUMAN] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
About this Structure
4nef is a 4 chain structure. Full crystallographic information is available from OCA.
