1o9w

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Template:STRUCTURE 1o9w

Contents

F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine

Template:ABSTRACT PUBMED 12864853

Function

[F17AG_ECOLX] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.

About this Structure

1o9w is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Buts L, Bouckaert J, De Genst E, Loris R, Oscarson S, Lahmann M, Messens J, Brosens E, Wyns L, De Greve H. The fimbrial adhesin F17-G of enterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain that binds N-acetylglucosamine. Mol Microbiol. 2003 Aug;49(3):705-15. PMID:12864853

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