1fiv

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Template:STRUCTURE 1fiv

Contents

STRUCTURE OF AN INHIBITOR COMPLEX OF PROTEINASE FROM FELINE IMMUNODEFICIENCY VIRUS

Template:ABSTRACT PUBMED 7664111

Function

[POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.

About this Structure

1fiv is a 2 chain structure with sequence from Feline immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

  • Wlodawer A, Gustchina A, Reshetnikova L, Lubkowski J, Zdanov A, Hui KY, Angleton EL, Farmerie WG, Goodenow MM, Bhatt D, et al.. Structure of an inhibitor complex of the proteinase from feline immunodeficiency virus. Nat Struct Biol. 1995 Jun;2(6):480-8. PMID:7664111

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