1q3g

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Template:STRUCTURE 1q3g

Contents 1 MurA (Asp305Ala) liganded with tetrahedral reaction intermediate 2 Function 3 About this Structure 4 See Also 5 Reference

MurA (Asp305Ala) liganded with tetrahedral reaction intermediate

Template:ABSTRACT PUBMED 13129913

Function

[MURA_ENTCL] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.

About this Structure

1q3g is a 16 chain structure with sequence from "aerobacter_cloacae"_(jordan_1890)_bergey_et_al._1923 "aerobacter cloacae" (jordan 1890) bergey et al. 1923. Full crystallographic information is available from OCA.

See Also

• Enoylpyruvate transferase

Reference

• Eschenburg S, Kabsch W, Healy ML, Schonbrunn E. A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states. J Biol Chem. 2003 Dec 5;278(49):49215-22. Epub 2003 Sep 16. PMID:13129913 doi:10.1074/jbc.M309741200