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1jq5

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Template:STRUCTURE 1jq5

Contents

Bacillus Stearothermophilus Glycerol dehydrogenase complex with NAD+

Template:ABSTRACT PUBMED 11566129

Function

[GLDA_GEOSE] Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates, such as propan-1,2-diol, butan-2,3-diol, ethan-1,2-diol, and 3-mercapto-1,2-dihydroxypropane.[1]

About this Structure

1jq5 is a 1 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  • Ruzheinikov SN, Burke J, Sedelnikova S, Baker PJ, Taylor R, Bullough PA, Muir NM, Gore MG, Rice DW. Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase. Structure. 2001 Sep;9(9):789-802. PMID:11566129
  1. ↑ Spencer P, Bown KJ, Scawen MD, Atkinson T, Gore MG. Isolation and characterisation of the glycerol dehydrogenase from Bacillus stearothermophilus. Biochim Biophys Acta. 1989 Feb 23;994(3):270-9. PMID:2493267

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