1nz6

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Template:STRUCTURE 1nz6

Contents 1 Crystal Structure of Auxilin J-Domain 2 Function 3 About this Structure 4 Reference

Crystal Structure of Auxilin J-Domain

Template:ABSTRACT PUBMED 12741832

Function

[AUXI_BOVIN] Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles.^[1]

About this Structure

1nz6 is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

• Jiang J, Taylor AB, Prasad K, Ishikawa-Brush Y, Hart PJ, Lafer EM, Sousa R. Structure-function analysis of the auxilin J-domain reveals an extended Hsc70 interaction interface. Biochemistry. 2003 May 20;42(19):5748-53. PMID:12741832 doi:10.1021/bi034270g

1. ↑ Fotin A, Cheng Y, Grigorieff N, Walz T, Harrison SC, Kirchhausen T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature. 2004 Dec 2;432(7017):649-53. Epub 2004 Oct 24. PMID:15502813 doi:10.1038/nature03078