4m36

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Template:STRUCTURE 4m36

Contents 1 Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7 2 Function 3 About this Structure 4 Reference

Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7

Template:ABSTRACT PUBMED 24726341

Function

[ANM7_TRYB2] Arginine methyltransferase that specifically catalyzes the formation of omega-N monomethylarginine (MMA). Has activity toward multiple substrates in vitro. Able to mediate the arginine methylation of histones and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.

About this Structure

4m36 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

• Wang C, Zhu Y, Caceres TB, Liu L, Peng J, Wang J, Chen J, Chen X, Zhang Z, Zuo X, Gong Q, Teng M, Hevel JM, Wu J, Shi Y. Structural Determinants for the Strict Monomethylation Activity by Trypanosoma brucei Protein Arginine Methyltransferase 7. Structure. 2014 Apr 8. pii: S0969-2126(14)00075-6. doi:, 10.1016/j.str.2014.03.003. PMID:24726341 doi:http://dx.doi.org/10.1016/j.str.2014.03.003