1ybg

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Template:STRUCTURE 1ybg

Contents 1 MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid 2 Function 3 About this Structure 4 See Also 5 Reference

MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid

Template:ABSTRACT PUBMED 15701635

Function

[MURA_ENTCL] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.

About this Structure

1ybg is a 4 chain structure with sequence from "aerobacter_cloacae"_(jordan_1890)_bergey_et_al._1923 "aerobacter cloacae" (jordan 1890) bergey et al. 1923. Full crystallographic information is available from OCA.

See Also

• Enoylpyruvate transferase

Reference

• Eschenburg S, Priestman MA, Abdul-Latif FA, Delachaume C, Fassy F, Schonbrunn E. A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA). J Biol Chem. 2005 Apr 8;280(14):14070-5. Epub 2005 Feb 8. PMID:15701635 doi:10.1074/jbc.M414412200