2e9s

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spinqualitylabelsall models PDB ID 2e9s Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2e9s, resolution 1.78Å ()
Ligands:	, ,
Gene:	RAB6B (HUMAN)
Related:	2fe4, 2ffq
Structural annotation: Resources: InterPro : Ipr003579, Ipr013753, Ipr001806, Ipr015600, Ipr005225 Pfam : PF00071 UniProt : Q9NRW1
Evolutionary conservation: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 human neuronal Rab6B in three intermediate forms 2 Function 3 About this Structure 4 Reference

human neuronal Rab6B in three intermediate forms

Template:ABSTRACT PUBMED 16790928

Function

[RAB6B_HUMAN] Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.^[1]

About this Structure

2e9s is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

• Garcia-Saez I, Tcherniuk S, Kozielski F. The structure of human neuronal Rab6B in the active and inactive form. Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):725-33. Epub 2006, Jun 20. PMID:16790928 doi:http://dx.doi.org/10.1107/S0907444906015319

1. ↑ Wanschers BF, van de Vorstenbosch R, Schlager MA, Splinter D, Akhmanova A, Hoogenraad CC, Wieringa B, Fransen JA. A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells. Exp Cell Res. 2007 Oct 1;313(16):3408-20. Epub 2007 Jul 17. PMID:17707369 doi:http://dx.doi.org/10.1016/j.yexcr.2007.05.032