1vfr

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Template:STRUCTURE 1vfr

Contents

THE MAJOR NAD(P)H:FMN OXIDOREDUCTASE FROM VIBRIO FISCHERI

Template:ABSTRACT PUBMED 9654450

Function

[FRA1_VIBFI] Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Major FMN reductase. It is capable of using both NADH and NADPH as electron donors. As electron acceptor, FMN is the most effective, FAD is considerably effective, and riboflavin is the least effective.

About this Structure

1vfr is a 2 chain structure with sequence from Aliivibrio fischeri. Full crystallographic information is available from OCA.

Reference

  • Koike H, Sasaki H, Kobori T, Zenno S, Saigo K, Murphy ME, Adman ET, Tanokura M. 1.8 A crystal structure of the major NAD(P)H:FMN oxidoreductase of a bioluminescent bacterium, Vibrio fischeri: overall structure, cofactor and substrate-analog binding, and comparison with related flavoproteins. J Mol Biol. 1998 Jul 10;280(2):259-73. PMID:9654450 doi:10.1006/jmbi.1998.1871

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