1upr

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Template:STRUCTURE 1upr

Contents 1 Crystal structure of the PEPP1 pleckstrin homology domain in complex with Inositol 1,3,4,5-tetrakisphosphate 2 Function 3 About this Structure 4 Reference

Crystal structure of the PEPP1 pleckstrin homology domain in complex with Inositol 1,3,4,5-tetrakisphosphate

Function

[PKHA4_HUMAN] Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.^[1]

About this Structure

1upr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

1. ↑ Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J. 2000 Oct 1;351(Pt 1):19-31. PMID:11001876