2ci1

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Template:STRUCTURE 2ci1

Contents 1 CRYSTAL STRUCTURE OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE I IN COMPLEX WITH S-NITROSO-LHOMOCYSTEINE 2 Function 3 About this Structure 4 Reference

CRYSTAL STRUCTURE OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE I IN COMPLEX WITH S-NITROSO-LHOMOCYSTEINE

Template:ABSTRACT PUBMED 16698551

Function

[DDAH1_BOVIN] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

About this Structure

2ci1 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

• Frey D, Braun O, Briand C, Vasak M, Grutter MG. Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors. Structure. 2006 May;14(5):901-11. PMID:16698551 doi:http://dx.doi.org/10.1016/j.str.2006.03.006