1sy0

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Template:STRUCTURE 1sy0

Contents 1 1.15 A Crystal Structure of T121V Mutant of Nitrophorin 4 from Rhodnius Prolixus 2 Function 3 About this Structure 4 Reference

1.15 A Crystal Structure of T121V Mutant of Nitrophorin 4 from Rhodnius Prolixus

Template:ABSTRACT PUBMED 15157102

Function

[NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).

About this Structure

1sy0 is a 1 chain structure with sequence from Rhopr. Full crystallographic information is available from OCA.

Reference

• Maes EM, Weichsel A, Andersen JF, Shepley D, Montfort WR. Role of binding site loops in controlling nitric oxide release: structure and kinetics of mutant forms of nitrophorin 4. Biochemistry. 2004 Jun 1;43(21):6679-90. PMID:15157102 doi:10.1021/bi049748a