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The suitability for chemical engineering of the highly symmetrical Mycobacterium tuberculosis dodecin was investigated, its inner cavity providing a large compartment shields introduced compounds from bulk solvent. Hybrids were obtained by S-alkylation of cysteine mutants and characterized by spectroscopic methods, including the crystal structures of wild type and biohybrid dodecins.
Chemical engineering of Mycobacterium tuberculosis dodecin hybrids.,Vinzenz X, Grosse W, Linne U, Meissner B, Essen LO Chem Commun (Camb). 2011 Oct 21;47(39):11071-3. Epub 2011 Sep 6. PMID:21897938[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Vinzenz X, Grosse W, Linne U, Meissner B, Essen LO. Chemical engineering of Mycobacterium tuberculosis dodecin hybrids. Chem Commun (Camb). 2011 Oct 21;47(39):11071-3. Epub 2011 Sep 6. PMID:21897938 doi:10.1039/c1cc12929e
