3t4s is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Cytokinins are classic hormones that orchestrate plant growth and development and the integrity of stem cell populations. Cytokinin receptors are eukaryotic sensor histidine kinases that are activated by both naturally occurring adenine-type cytokinins and urea-based synthetic compounds. Crystal structures of the Arabidopsis thaliana histidine kinase 4 sensor domain in complex with different cytokinin ligands now rationalize the hormone-binding specificity of the receptor and may spur the design of new cytokinin ligands.
Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.,Hothorn M, Dabi T, Chory J Nat Chem Biol. 2011 Oct 2;7(11):766-8. doi: 10.1038/nchembio.667. PMID:21964459[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Hothorn M, Dabi T, Chory J. Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4. Nat Chem Biol. 2011 Oct 2;7(11):766-8. doi: 10.1038/nchembio.667. PMID:21964459 doi:10.1038/nchembio.667
