3ujm is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7A resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised of a beta-sheet and three alpha-helices forming a cone-like shape. However, known binding sites for RanGDP and FxFG containing peptides show electrostatic and steric differences compared to nuclear transport factor 2. A HEPES molecule bound in the structure suggests a new, and possibly physiologically relevant, ligand binding site.
Crystal structure of the Rasputin NTF2-like domain from Drosophila melanogaster.,Vognsen T, Kristensen O Biochem Biophys Res Commun. 2012 Mar 30;420(1):188-92. Epub 2012 Mar 3. PMID:22414690[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Vognsen T, Kristensen O. Crystal structure of the Rasputin NTF2-like domain from Drosophila melanogaster. Biochem Biophys Res Commun. 2012 Mar 30;420(1):188-92. Epub 2012 Mar 3. PMID:22414690 doi:10.1016/j.bbrc.2012.02.140
