Function
Acyl carrier protein (ACP) is a component of the fatty acid biosynthesis cycle. ACP catalyzes the addition of a thioester to a phosphopantetheine moiety. This moiety is added post-translationally to ACP serine residue by ACP synthetase (ACPS).
Disease
Relevance
Structural highlights
3D structures of acyl carrier protein
Updated on 17-June-2014
Acyl carrier protein
1l0h, 1t8k – EcACP – Escherichia coli
1l0i – EcACP (mutant)
1hy8 – BsACP – Bacillus subtilis
1vku – ACP – Thermotoga maritima
1x3o – ACP – Thermus thermophilus
2fq0, 3gzl, 3gzm – PfACP – Plasmodium falciparum
2qnw – ACP residues 100-180 – Toxoplasma gondii
2ehs, 2eht – ACP – Aquifex aeolicus
3ce7 – ACP – Toxoplasma
Acyl carrier protein NMR structures
2kwl – ACP – Borrelia burgdorferi - NMR
2l0q – ACP (mutant) – Vibrio harveyi - NMR
2l3v – ACP – Brucella melitensis - NMR
2l4b – ACP – Anaplasma phagocytophilum - NMR
2lol – ACP – Rickettsia prowazekii - NMR
1acp, 2k92, 2k93, 2k94 – EcACP - NMR
1or5 – ACP – Streptomyces roseofulvus - NMR
2fq2 – PfACP - NMR
2cnr – ScACP – Streptomyces coelicolor - NMR
Acyl carrier protein complex with fatty acid
2fac, 2fad, 2fae – EcACP + thioester
2koo, 2kop, 2koq, 2kor, 2kos – ScACP + thioester - NMR
2x2b – EcACP + malonate derivative
Acyl carrier protein complex with protein
2fhs – EcACP + enoyl-[ACP] reductase
3ejb, 3ejd, 3eje – EcACP + thioester + p450BioI
3ny7 – EcACP + YchM STAS domain
1f80 – BsACP + ACPS
4dxe – ACP + ACPS – Staphylococcus aureus
4etw – ACP + pimelyl-[ACP] methyl ester esterase – Shigella flexneri
4ihf, 4ihg, 4ihh – EcACP + protein FIRA
4keh – EcACP + fatty acid dehydratase
References
