Function
Intercellular adhesion molecule (ICAM) is part of the immunoglobulin superfamily. ICAM binds to LFA-1 and macrophage-1 antigen during inflammation. ICAM contains 5 Ig-like domains.
Disease
Relevance
Structural highlights
3D structures of intercellular adhesion molecule
Updated on 06-July-2014
ICAM-1 (CD54)
1iam, 1ic1, 1d3l – hICAM N terminal domain – human
1p53 – hICAM domain 3-5
ICAM-1 complexes
1d3e, 1d3i – hICAM N terminal domain + rhinovirus coat proteins - CryoEM
1mq8 – hICAM domain 1-2 + LFA-1
3tcx – hICAM domain 1 + LFA-1
1z7z – hICAM domain 1-5 + coxsakievirus coat proteins - CryoEM
2qz4 – hICAM domain 4 + antibody
ICAM-2
1zxq – hICAM extracellular domain
ICAM-3
1t0p – hICAM N terminal domain + LFA-1
ICAM-5
3bn3 – hICAM N terminal domain + LFA-1
References
