1cmf

From Proteopedia

Revision as of 08:26, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:1cmf.gif


PDB ID 1cmf

Drag the structure with the mouse to rotate
Coordinates: save as pdb, mmCIF, xml



NMR SOLUTION STRUCTURE OF APO CALMODULIN CARBOXY-TERMINAL DOMAIN


Overview

We have determined the solution structures of the apo and (Ca2+)2 forms of the carboxy-terminal domain of calmodulin using multidimensional heteronuclear nuclear magnetic resonance spectroscopy. The results show that both forms adopt well-defined structures with essentially equal secondary structure. A comparison of the structures of the two forms shows that Ca2+ binding causes major rearrangements of the secondary structure elements with changes in inter-residue distances of up to 15 A and exposure of the hydrophobic interior of the four-helix bundle. Comparisons with previously determined high-resolution X-ray structures and models of calmodulin indicate that this domain is structurally autonomous.

About this Structure

1CMF is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Calcium-induced structural changes and domain autonomy in calmodulin., Finn BE, Evenas J, Drakenberg T, Waltho JP, Thulin E, Forsen S, Nat Struct Biol. 1995 Sep;2(9):777-83. PMID:7552749

Page seeded by OCA on Thu Mar 20 10:26:10 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cmf"
Personal tools