1a4f is a 2 chain structure with sequence from Anser indicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
We have determined the crystal structure of bar-headed goose haemoglobin in the oxy form to a resolution of 2.0 A. The R-factor of the model is 19.8%. The structure is similar to human HbA, but contacts between the subunits show slightly altered packing of the tetramer. Bar-headed goose blood shows a greatly elevated oxygen affinity compared to closely related species of geese. This is apparently due to a single proline to alanine mutation at the alpha 1 beta 1 interface which destabilises the T state of the protein. The beta chain N and C termini are well-localized, and together with other neighbouring basic groups they form a strongly positively charged groove at the entrance to the central cavity around the molecular dyad. The well-ordered conformation and the three-dimensional distribution of positive charges clearly indicate this area to be the inositol pentaphosphate binding site of bird haemoglobins.
The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form).,Zhang J, Hua Z, Tame JR, Lu G, Zhang R, Gu X J Mol Biol. 1996 Jan 26;255(3):484-93. PMID:8568892[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
↑ Zhang J, Hua Z, Tame JR, Lu G, Zhang R, Gu X. The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form). J Mol Biol. 1996 Jan 26;255(3):484-93. PMID:8568892 doi:http://dx.doi.org/10.1006/jmbi.1996.0040
