1dir

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Image:1dir.gif


PDB ID 1dir

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, resolution 2.60Å
Ligands:
Activity: 6,7-dihydropteridine reductase, with EC number 1.5.1.34
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER


Overview

A binary complex of dihydropteridine reductase and NADH crystallizes in the space group C2, with a = 222.2, b = 46.5, c = 95.3 A and beta = 101.1 degrees. There are two dimers in the asymmetric unit. The structure was solved by molecular-replacement techniques and refined with 2.6 A data to a crystallographic R factor of 16.8%. Each dimer has twofold non-crystallographic symmetry and the four individual monomers in the asymmetric unit have the same overall molecular conformation.

About this Structure

1DIR is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver., Su Y, Skinner MM, Xuong NH, Matthews DA, Whiteley JM, Varughese KI, Acta Crystallogr D Biol Crystallogr. 1994 Nov 1;50(Pt 6):884-8. PMID:15299357

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