Catenin
From Proteopedia
Catenins (CTN) are proteins which make complexes with cadherin.
- α-CTN links cadherin (CDH) and α-actinin, it is encoded by 3 genes: α-E-CTN (epithelial), α-T-CTN (membrane bound), and α-N-CTN (neuronal).
- β-CTN is a subunit of the cadherin complex. It contains Armadillo repeats which are a pair of helices forming hairpin structure.
- γ-CTN (or plakoglobin) is a component of desmosomes and contains armadillo repeats.
- δ-CTN is expressed in the brain and contains 10 armadillo repeats.
- p120 CTN is another member of the CTN family.
Contents |
3D Structures of Catenin
Updated on 25-August-2014
P120 CTN
3l6x, 3l6y – p120 CTN (mutant) +E-CDH – human
α-CTN
4k1n - mα-CTN - mouse
1l7c, 4k1o – mα-CTN C-terminal
4igg - hα-CTN
1h6g - hα-CTN M domain
1dov - mα-CTN dimerization domain
1dow - mα-CTN dimerization domain+ mβ-CTN chimera
4ehp - hα-CTN residues 277-382 + vinculin head domain
β-CTN
3diw – mβ-CTN C-terminal+Tax interaction protein 1
2z6g - β-CTN – zebrafish
4ev8, 4ev9, 4eva, 4evp, 4evt - mβ-CTN
2z6h - hβ-CTN C-terminal
2gl7 - hβ-CTN (mutant)+TCF-4+B-cell lymphoma protein
3sl9 - hβ-CTN +B-cell lymphoma protein 9
3sla - hβ-CTN repeats 1-4
3tx7 - hβ-CTN + nuclear receptor LRH-1
2g57 - β-CTN fragment – NMR
3bct, 2bct - mβ-CTN armadillo repeats
1v18 - mβ-CTN armadillo repeats+apc protein
1t08 - hβ-CTN armadillo repeats+apc protein+ hβ-CTN interacting protein
1th1 - hβ-CTN armadillo repeats+apc protein
1qz7 - hβ-CTN armadillo repeats+axis inhibition protein
1g3j - hβ-CTN armadillo repeats+TCF3-CBD
1p22 - hβ-CTN +skp1+trcp1
1luj - hβ-CTN C-terminal+ hβ-CTN interacting protein
1jdh, 1jpw - hβ-CTN C-terminal+HTCF-4
4djs - hβ-CTN armadillo repeats + peptide inhibitor
1m1e - mβ-CTN armadillo repeats + mβ-CTN interacting protein
1jpp - mβ-CTN armadillo repeats+apc protein
1i7x, 1i7w - mβ-CTN armadillo repeats+E-CDH
3ouw, 3oux - mβ-CTN+lymphoid enhancer-binding factor 1
γ-CTN
3ifq – hγ-CTN+E-CDH EC1+EC2+EC3
