Elastase

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Template:STRUCTURE 1esa

Elastase (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation. For additional details see Serine Proteases.

Contents

3D structures of elastase

Updated on 27-August-2014

MMP12

Matrix metalloproteinase

MMP16

Matrix metalloproteinase

ELA1

3mty, 3mu0, 3mu1, 3mu4, 3mu5, 3mu8, 3mnb, 3mnc, 3mns, 3mnx, 3mo3, 3mo6, 3mo9, 3moc, 3e3t, 2v0b, 2g4t, 2g4u, 2de8, 2blo, 2blq, 2a7c, 2a7j, 1gvk, 1qnj, 1lvy, 3est, 1est, 2oqu, 3odd, 3odf, 2bdc – pELA1 – pig
3hgn – pELA1+peptidyl inhibitor – neutron
3hgp, 2cv3, 2bdb, 2bcd, 2h1u, 1mmj, 1h9l, 1nes, 4est, 5est, 8est, 7est, 6est - pELA1+peptidyl inhibitor
1fzz – pELA1+ONO-6818
1qr3, 1qgf, 1bru, 1hv7, 1btu – pELA1+cyclic inhibitor
1okx – pELA1 + scyptolin
1e34, 1e35, 1e36, 1e37, 1e38 – pELA1-gamma-lactam
1eai – pELA1+Ascaris inhibitor
2d26 – pELA1+α-1-antitrypsin
1fle – pELA1+elafin
1b0e, 1b0f – pELA1+MDL
2v35 – pELA1+JM54
2iot – pELA1+clavulanic acid
2de9 – pELA1+tris
1uvo, 1uvp, 1lka, 1lkb – pELA1+ions
1gwa – pELA1+I3
1uo6, 1c1m – pELA1+Xe
1l0z, 1l1g - pELA1+Xe+Br
2bb4, 2bd2, 2bd3, 2bd4, 2bd5, 2bd7, 2bd8, 2bd9, 1hax, 1hay, 1haz, 1hb0, 1qix – pELA1+beta-casomorphin-7
2bda – pELA1+N-acetyl-NPI
1mcv – pELA1+squash inhibitor
1bma – pELA1+aminimide
1elf, 1elg – pELA1+peptidyl hydroxylamine
1eld, 1ele, 1elb, 1ela, 1elc, 2est – pELA1+anilide inhibitor
1esa, 1esb – pELA1 intermediate
1eas, 1eat, 1eau – pELA1+pyridine inhibitor
1inc – pELA1+benzoxazinone
1jim, 9est, 8est – pELA1+coumarin derivative
2fo9, 2foa, 2fob, 2foc, 2fod, 2foe, 2fof, 2fog, 2foh – pELA1+solvent
3dbk – PaELA+phophoramidon – Pseudomonas aeruginosa
1u4g – PaELA+HPI
1ezm - PaELA
1elt – ELA - salmon

ELA2

3q76 – hELA2
3q77 – hELA2+dihydropyrimidone inhibitor
2z7f – hELA2 peptidase domain +antileukoproteinase
2rg3 – hELA2+sulfonic inhibitor
1h1b, 1ppg, 1hne – hELA2+inhibitor
1ppf – hELA2+ovomucoid
1b0f – hELA2+MDL101146

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Michal Harel, Alexander Berchansky, Guido Hansen, Jaime Prilusky

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