1cmi is a 4 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1b1w. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The structure of the protein known both as neuronal nitric oxide synthase inhibitory protein, PIN (protein inhibitor of nNOS), and also as the 8 kDa dynein light chain (LC8) has been solved by X-ray diffraction. Two PIN/LC8 monomers related by a two-fold axis form a rectangular dimer. Two pairs of alpha-helices cover opposite faces, and each pair of helices packs against a beta-sheet with five antiparallel beta-strands. Each five-stranded beta-sheet contains four strands from one monomer and a fifth strand from the other monomer. A 13-residue peptide from nNOS is bound to the dimer in a deep hydrophobic groove as a sixth antiparallel beta-strand. The structure provides key insights into dimerization of and peptide binding by the multifunctional PIN/LC8 protein.
Structure of the PIN/LC8 dimer with a bound peptide.,Liang J, Jaffrey SR, Guo W, Snyder SH, Clardy J Nat Struct Biol. 1999 Aug;6(8):735-40. PMID:10426949[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Liang J, Jaffrey SR, Guo W, Snyder SH, Clardy J. Structure of the PIN/LC8 dimer with a bound peptide. Nat Struct Biol. 1999 Aug;6(8):735-40. PMID:10426949 doi:10.1038/11501
