Leukotriene A4 Hydrolase

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Template:STRUCTURE 2xpz

Leukotriene A4 Hydrolase (LTA4H) is an aminopeptidase which converts leukotriene A4 to leukotriene B4 as part of the arachidonic acid metabolism.

3D Structures of Leukotriene A4 Hydrolase

Updated on 02-September-2014

LTA4H

1xpy, 2xpz – yLTA4H – yeast
1sqm, 1gw6, 1h19 - hLTA4H (mutant) - human

LTA4H + inhibitor

2xq0 – yLTA4H+bestatin
3fh5, 3fh7, 3fh8, 3fhe, 3ful, 3fum, 3fun - hLTA4H+pyrrolidine inhibitor 1hs6 - hLTA4H+bestatin
3ftz, 3ftv, 3ftw, 3ftx, 3fui - hLTA4H+aniline derivative
3fts, 3ftu - hLTA4H+resveratrol derivative
3fty, 3fu0 - hLTA4H+pyridine derivative
3fu3, 3fu5, 3fu6, 3fud - hLTA4H+thio derivative
3fue, 3fuf, 3fuh - hLTA4H+bestatin+indole derivative
3fuj, 3fuk - hLTA4H+indole derivative
3b7r, 3cho, 3chp, 3chq, 3chr, 3chs, 2r59, 3u9w - hLTA4H+inhibitor
3b7u - hLTA4H+kelatorphan
2vj8 - hLTA4H+hydroxamic acid
4dpr – hLTA4H + captopril
3b7s, 3b7t - hLTA4H (mutant)+tripeptide

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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