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1huu
From Proteopedia
Revision as of 08:49, 28 September 2014 by OCA (Talk | contribs)
1huu is a 3 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The prokaryotic protein HU, integration host factor (IHF) from Escherichia coli, and transcription factor 1 (TF1) from bacteriophage SPO1 are closely related molecules. Biochemical results suggest that the role of these proteins is to bind and bend DNA. From the high-resolution structure of HU, we propose a model for this interaction with DNA. Crucial amino acid differences between the proteins can be rationalized in terms of their different specific functions.
A protein structural motif that bends DNA.,White SW, Appelt K, Wilson KS, Tanaka I Proteins. 1989;5(4):281-8. PMID:2508086[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
