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1fer
From Proteopedia
Revision as of 12:01, 28 September 2014 by OCA (Talk | contribs)
1fer is a 1 chain structure with sequence from Azotobacter vinelandii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
Ferredoxin I from Azotobacter vinelandii (AvFdI) is an iron-sulfur protein composed of 106 amino acids, seven Fe atoms and eight inorganic S* atoms. A crystallographic redetermination of its structure showed the originally reported structure to be incorrect. We report here the crystal structure of AvFdI at pH 6.5. Extensive refinement has led to a final R value of 0.170 for all 6986 non-extinct reflections in the range 10-2.3 A using a solvent model which includes 98 discrete solvent atoms with occupancies between 0.3 and 1.0 and an average B value of 22.5 A(2). The first half of the peptide chain closely resembles that of the 55-residue ferredoxin from Peptococcus aerogenes (PaFd), while the remainder consists of three turns of helix and a series of loops which form a cap over part of the molecular core. Despite the similarities in structure and surroundings, the corresponding 4Fe4S* clusters in PaFd and AvFdI have strikingly different redox potentials; a possible explanation has been sought in the differing hydration models for the two molecules.
Structure at pH 6.5 of ferredoxin I from Azotobacter vinelandii at 2.3 A resolution.,Merritt EA, Stout GH, Turley S, Sieker LC, Jehsen LH, Orme-Johnson WH Acta Crystallogr D Biol Crystallogr. 1993 Mar 1;49(Pt 2):272-81. PMID:15299532[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
↑ Merritt EA, Stout GH, Turley S, Sieker LC, Jehsen LH, Orme-Johnson WH. Structure at pH 6.5 of ferredoxin I from Azotobacter vinelandii at 2.3 A resolution. Acta Crystallogr D Biol Crystallogr. 1993 Mar 1;49(Pt 2):272-81. PMID:15299532 doi:10.1107/S0907444992007248
