1mnm is a 6 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The structure of a complex containing the homeodomain repressor protein MATalpha2 and the MADS-box transcription factor MCM1 bound to DNA has been determined by X-ray crystallography at 2.25 A resolution. It reveals the protein-protein interactions responsible for cooperative binding of MATalpha2 and MCM1 to DNA. The otherwise flexible amino-terminal extension of the MATalpha2 homeodomain forms a beta-hairpin that grips the MCM1 surface through parallel beta-strand hydrogen bonds and close-packed, predominantly hydrophobic, side chains. DNA bending induced by MCM1 brings the two proteins closer together, facilitating their interaction. An unusual feature of the complex is that an eight-amino-acid sequence adopts an alpha-helical conformation in one of two copies of the MATalpha2 monomer and a beta-strand conformation in the other. This 'chameleon' sequence of MATalpha2 may be important for recognizing natural operator sites.
Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex.,Tan S, Richmond TJ Nature. 1998 Feb 12;391(6668):660-6. PMID:9490409[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Tan S, Richmond TJ. Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex. Nature. 1998 Feb 12;391(6668):660-6. PMID:9490409 doi:10.1038/35563
