Publication Abstract from PubMed
The structure of the recombinant Escherichia coli protein YbcJ, a representative of a conserved family of bacterial proteins (COG2501), was determined by nuclear magnetic resonance. The fold of YbcJ identified it as a member of the larger family of S4-like RNA binding domains. These domains bind to structured RNA, such as that found in tRNA, rRNA, and a pseudoknot of mRNA. The structure of YbcJ revealed a highly conserved patch of basic residues, comprising amino acids K26, K38, R55, K56, and K59, which likely participate in RNA binding.
The solution structure of YbcJ from Escherichia coli reveals a recently discovered alphaL motif involved in RNA binding.,Volpon L, Lievre C, Osborne MJ, Gandhi S, Iannuzzi P, Larocque R, Cygler M, Gehring K, Ekiel I J Bacteriol. 2003 Jul;185(14):4204-10. PMID:12837795[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
