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1z7k
From Proteopedia
Revision as of 22:12, 28 September 2014 by OCA (Talk | contribs)
1z7k is a 3 chain structure with sequence from Meleagris gallopavo and Sus scrofa. This structure supersedes the now removed PDB entry 1r0t. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
Crystal structure of the complex between porcine beta-trypsin and the second domain of the Kazal-type ovomucoid turkey egg white trypsin inhibitor (OMTKY2) has been determined at 1.9A resolution. A peptide fragment from the first domain has been crystallized with the complex. Restrained-refinement of the structure led to an R-factor of 0.19 for the 32206 reflections. OMTKY2 exhibits the canonical Kazal-type fold with a central alpha-helix and a short two-stranded anti-parallel beta-sheet. The carbonyl carbon of the reactive site prefers trigonal geometry. The reactive site loop geometry of the inhibitor is complementary to the surface and charge of the binding site in beta-trypsin.
Crystal structure of trypsin-turkey egg white inhibitor complex.,Ibrahim BS, Pattabhi V Biochem Biophys Res Commun. 2004 Jan 2;313(1):8-16. PMID:14672690[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
↑ Ibrahim BS, Pattabhi V. Crystal structure of trypsin-turkey egg white inhibitor complex. Biochem Biophys Res Commun. 2004 Jan 2;313(1):8-16. PMID:14672690
