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2kk7
From Proteopedia
Revision as of 06:05, 29 September 2014 by OCA (Talk | contribs)
2kk7 is a 1 chain structure with sequence from Methanocaldococcus jannaschii. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
The N-termini of E and H of A1AO ATP synthase have been shown to interact and an NMR structure of N-terminal H1-47 has been solved recently. In order to understand the E-H assembly and the N-terminal structure of E, the truncated construct E1-52 of Methanocaldococcus jannaschii A1AO ATP synthase was produced, purified and the solution structure of E1-52 was determined by NMR spectroscopy. The protein is 60.5 A in length and forms an alpha helix between the residues 8-48. The molecule is amphipathic with a strip of hydrophobic residues, discussed as a possible helix-helix interaction with neighboring subunit H.
NMR solution structure of the N-terminal domain of subunit E (E1-52) of A1AO ATP synthase from Methanocaldococcus jannaschii.,Gayen S, Balakrishna AM, Gruber G J Bioenerg Biomembr. 2009 Aug;41(4):343-8. PMID:19760172[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
↑ Gayen S, Balakrishna AM, Gruber G. NMR solution structure of the N-terminal domain of subunit E (E1-52) of A1AO ATP synthase from Methanocaldococcus jannaschii. J Bioenerg Biomembr. 2009 Aug;41(4):343-8. PMID:19760172 doi:10.1007/s10863-009-9237-3
